Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity

Recent studies have demonstrated that many parasites release extracellular vesicles (EVs), yet little is known about the specific interactions of EVs with immune cells or their functions during infection. We show that EVs secreted by the gastrointestinal nematode Heligmosomoides polygyrus are intern...

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Опубликовано в: :Cell Rep
Главные авторы: Coakley, Gillian, McCaskill, Jana L., Borger, Jessica G., Simbari, Fabio, Robertson, Elaine, Millar, Marissa, Harcus, Yvonne, McSorley, Henry J., Maizels, Rick M., Buck, Amy H.
Формат: Artigo
Язык:Inglês
Опубликовано: Cell Press 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457486/
https://ncbi.nlm.nih.gov/pubmed/28538175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.001
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