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Site-Directed Mutagenesis Analysis of Amino Acids Critical for Activity of the Type I Signal Peptidase of the Archaeon Methanococcus voltae

Site-directed mutagenesis studies of the signal peptidase of the methanogenic archaeon Methanococcus voltae identified three conserved residues (Ser(52), His(122), and Asp(148)) critical for activity. The requirement for one conserved aspartic acid residue distinguishes the archaeal enzyme from both...

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Main Authors: Bardy, Sonia L., Ng, Sandy Y. M., Carnegie, David S., Jarrell, Ken F.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC545723/
https://ncbi.nlm.nih.gov/pubmed/15659694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.3.1188-1191.2005
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