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Site-Directed Mutagenesis Analysis of Amino Acids Critical for Activity of the Type I Signal Peptidase of the Archaeon Methanococcus voltae

Site-directed mutagenesis studies of the signal peptidase of the methanogenic archaeon Methanococcus voltae identified three conserved residues (Ser(52), His(122), and Asp(148)) critical for activity. The requirement for one conserved aspartic acid residue distinguishes the archaeal enzyme from both...

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Bibliografiske detaljer
Main Authors: Bardy, Sonia L., Ng, Sandy Y. M., Carnegie, David S., Jarrell, Ken F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC545723/
https://ncbi.nlm.nih.gov/pubmed/15659694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.3.1188-1191.2005
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