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Site-Directed Mutagenesis Analysis of Amino Acids Critical for Activity of the Type I Signal Peptidase of the Archaeon Methanococcus voltae

Site-directed mutagenesis studies of the signal peptidase of the methanogenic archaeon Methanococcus voltae identified three conserved residues (Ser(52), His(122), and Asp(148)) critical for activity. The requirement for one conserved aspartic acid residue distinguishes the archaeal enzyme from both...

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Detalhes bibliográficos
Main Authors: Bardy, Sonia L., Ng, Sandy Y. M., Carnegie, David S., Jarrell, Ken F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545723/
https://ncbi.nlm.nih.gov/pubmed/15659694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.3.1188-1191.2005
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