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Combined Inactivation and Expression Strategy To Study Gene Function under Physiological Conditions: Application to Identification of New Escherichia coli Adhesins

In bacteria, whereas disruption methods have been improved recently, the use of plasmid complementation strategies are still subject to limitations, such as cloning difficulties, nonphysiological levels of gene expression, or a requirement for antibiotics as plasmid selection pressure. Moreover, bec...

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Detalhes bibliográficos
Main Authors: Roux, Agnès, Beloin, Christophe, Ghigo, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545717/
https://ncbi.nlm.nih.gov/pubmed/15659678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.3.1001-1013.2005
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