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miR-148a-mediated estrogen-induced cholestasis in intrahepatic cholestasis of pregnancy: Role of PXR/MRP3

Intrahepatic cholestasis of pregnancy (ICP) is an idiopathic liver disease while the biochemical characteristic is the elevated level of total bile acid (TBA). The present study investigated whether miR-148a mediates the induced effect of estrogen on the development of ICP and the proper mechanism:...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Rao, Zhou-Zhou, Zhang, Xiao-Wen, Ding, Yi-Ling, Yang, Meng-Yuan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457162/
https://ncbi.nlm.nih.gov/pubmed/28575098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178702
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