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Evidence for a Novel, Caspase-8-Independent, Fas Death Domain-Mediated Apoptotic Pathway

Certain caspase-8 null cell lines demonstrate resistance to Fas-induced apoptosis, indicating that the Fas/FasL apoptotic pathway may be caspase-8-dependent. Some reports, however, have shown that Fas induces cell death independent of caspase-8. Here we provide evidence for an alternative, caspase-8...

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Bibliografiske detaljer
Main Authors: Feng, Hanping, Zeng, Yi, Graner, Michael W., Whitesell, Luke, Katsanis, Emmanuel
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC545657/
https://ncbi.nlm.nih.gov/pubmed/15123887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/S1110724304308041
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