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Adaptation of Candida albicans to environmental pH induces cell wall remodelling and enhances innate immune recognition

Candida albicans is able to proliferate in environments that vary dramatically in ambient pH, a trait required for colonising niches such as the stomach, vaginal mucosal and the GI tract. Here we show that growth in acidic environments involves cell wall remodelling which results in enhanced chitin...

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Publicat a:PLoS Pathog
Autors principals: Sherrington, Sarah L., Sorsby, Eleanor, Mahtey, Nabeel, Kumwenda, Pizga, Lenardon, Megan D., Brown, Ian, Ballou, Elizabeth R., MacCallum, Donna M., Hall, Rebecca A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456412/
https://ncbi.nlm.nih.gov/pubmed/28542528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006403
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