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Adaptation of Candida albicans to environmental pH induces cell wall remodelling and enhances innate immune recognition

Candida albicans is able to proliferate in environments that vary dramatically in ambient pH, a trait required for colonising niches such as the stomach, vaginal mucosal and the GI tract. Here we show that growth in acidic environments involves cell wall remodelling which results in enhanced chitin...

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Pubblicato in:PLoS Pathog
Autori principali: Sherrington, Sarah L., Sorsby, Eleanor, Mahtey, Nabeel, Kumwenda, Pizga, Lenardon, Megan D., Brown, Ian, Ballou, Elizabeth R., MacCallum, Donna M., Hall, Rebecca A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456412/
https://ncbi.nlm.nih.gov/pubmed/28542528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006403
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