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A Defect in the Acetyl Coenzyme A↔Acetate Pathway Poisons Recombinational Repair-Deficient Mutants of Escherichia coli

Recombinational repair-dependent mutants identify ways to avoid chromosomal lesions. Starting with a recBC(Ts) strain of Escherichia coli, we looked for mutants unable to grow at 42°C in conditions that inactivate the RecBCD(Ts) enzyme. We isolated insertions in ackA and pta, which comprise a two-ge...

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Detalhes bibliográficos
Main Authors: Shi, Idina Y., Stansbury, John, Kuzminov, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545612/
https://ncbi.nlm.nih.gov/pubmed/15687190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.4.1266-1275.2005
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