Peripheral K(V)7 channels regulate visceral sensory function in mouse and human colon

BACKGROUND: Chronic visceral pain is a defining symptom of many gastrointestinal disorders. The K(V)7 family (K(V)7.1–K(V)7.5) of voltage-gated potassium channels mediates the M current that regulates excitability in peripheral sensory nociceptors and central pain pathways. Here, we use a combinatio...

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Vydáno v:Mol Pain
Hlavní autoři: Peiris, Madusha, Hockley, James RF, Reed, David E, Smith, Ewan St. John, Bulmer, David C, Blackshaw, L Ashley
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456027/
https://ncbi.nlm.nih.gov/pubmed/28566000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806917709371
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