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Growth Factors, aging and age-related diseases

Simple organisms including yeast and flies with mutations in the IGF-1 and Tor-S6K pathways are dwarfs, are highly protected from toxins, and survive up to 3 times longer. Similarly, dwarf mice with deficiencies in the growth hormone-IGF-I axis are also long-lived and protected from diseases. We rec...

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Detalhes bibliográficos
Publicado no:Growth Horm IGF Res
Main Authors: Balasubramanian, Priya, Longo, Valter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455771/
https://ncbi.nlm.nih.gov/pubmed/26883276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2016.01.001
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