The Histone Deacetylase Inhibitor JAHA Down-Regulates pERK and Global DNA Methylation in MDA-MB231 Breast Cancer Cells

The histone deacetylase inhibitor N(1)-(ferrocenyl)-N(8)-hydroxyoctanediamide (JAHA) down-regulates extracellular-signal-regulated kinase (ERK) and its activated form in triple-negative MDA-MB231 breast cancer cells after 18 h and up to 30 h of treatment, and to a lesser extent AKT and phospho-AKT a...

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Bibliografiske detaljer
Udgivet i:Materials (Basel)
Main Authors: Librizzi, Mariangela, Chiarelli, Roberto, Bosco, Liana, Sansook, Supojjanee, Gascon, Jose M., Spencer, John, Caradonna, Fabio, Luparello, Claudio
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455366/
https://ncbi.nlm.nih.gov/pubmed/28793617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma8105358
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