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Dissecting the molecular control of endothelial NO synthase by caveolin-1 using cell-permeable peptides
In endothelia, NO is synthesized by endothelial NO synthase (eNOS), which is negatively regulated by caveolin-1 (Cav-1), the primary coat protein of caveolae. We show that delivery of Cav-1 amino acids 82-101 (Cav) fused to an internalization sequence from Antennapedia (AP) blocks NO release in vitr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC545535/ https://ncbi.nlm.nih.gov/pubmed/15637154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407224102 |
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