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Design of an Artificial Glycosidase - Metallopeptides that Remove H-Antigen from Human Erythrocytes

Catalysts that promote carbohydrate degradation are of wide potential application, but the use of either enzyme glycosidases or small-molecule catalysts in biological systems raises significant challenges. Herein we demonstrate a novel strategy for the design of synthetic agents that mimic natural g...

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Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Yu, Zhen, Cowan, J. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455340/
https://ncbi.nlm.nih.gov/pubmed/28128528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201612079
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