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Suboptimal Dosing Parameters as Possible Factors in the Negative Phase III Clinical Trials of Progesterone for Traumatic Brain Injury

To date, outcomes for all Phase III clinical trials for traumatic brain injury (TBI) have been negative. The recent disappointing results of the Progesterone for the Treatment of Traumatic Brain Injury (ProTECT) and Study of a Neuroprotective Agent, Progesterone, in Severe Traumatic Brain Injury (Sy...

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Vydáno v:J Neurotrauma
Hlavní autoři: Howard, Randy B., Sayeed, Iqbal, Stein, Donald G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455214/
https://ncbi.nlm.nih.gov/pubmed/26370183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2015.4179
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