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Simple adjustment of the sequence weight algorithm remarkably enhances PSI-BLAST performance
BACKGROUND: PSI-BLAST, an extremely popular tool for sequence similarity search, features the utilization of Position-Specific Scoring Matrix (PSSM) constructed from a multiple sequence alignment (MSA). PSSM allows the detection of more distant homologs than a general amino acid substitution matrix...
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| Veröffentlicht in: | BMC Bioinformatics |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5455086/ https://ncbi.nlm.nih.gov/pubmed/28578660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1686-9 |
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