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The Impact of SMAD4 Loss on Outcome in Patients with Advanced Pancreatic Cancer Treated with Systemic Chemotherapy

The role of the tumor suppressor mothers against decapentaplegic homolog 4 (SMAD4) has not yet been defined in patients (pts) with advanced pancreatic cancer (aPC). This translational research study was designed to evaluate the impact of tumoral SMAD4 loss on clinicopathological parameters and outco...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ormanns, Steffen, Haas, Michael, Remold, Anna, Kruger, Stephan, Holdenrieder, Stefan, Kirchner, Thomas, Heinemann, Volker, Boeck, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455003/
https://ncbi.nlm.nih.gov/pubmed/28534865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051094
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