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Upregulated Autophagy in Sertoli Cells of Ethanol-Treated Rats Is Associated with Induction of Inducible Nitric Oxide Synthase (iNOS), Androgen Receptor Suppression and Germ Cell Apoptosis

This study was conducted to investigate the autophagic response of Sertoli cells (SCs) to acute ethanol toxicity using in vivo and in vitro models. Adult Wistar rats were intraperitoneally injected with either 5 g/kg ethanol or phosphate-buffered saline (for the control group) and sacrificed 0, 3, 6...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Horibe, Akio, Eid, Nabil, Ito, Yuko, Hamaoka, Hitomi, Tanaka, Yoshihisa, Kondo, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454973/
https://ncbi.nlm.nih.gov/pubmed/28505146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051061
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