Laminin α1 globular domains 4–5 induce fetal development but are not vital for embryonic basement membrane assembly

During early mouse embryogenesis, each laminin (Lm) chain of the first described Lm, a heterotrimer of α1, β1, and γ1 chains (Lm-1), is essential for basement membrane (BM) assembly, which is required for pregastrulation development. Individual domains may have other functions, not necessarily struc...

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Bibliographic Details
Main Authors: Schéele, Susanne, Falk, Mats, Franzén, Ahnders, Ellin, Fredrik, Ferletta, Maria, Lonai, Peter, Andersson, Björn, Timpl, Rupert, Forsberg, Erik, Ekblom, Peter
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC545491/
https://ncbi.nlm.nih.gov/pubmed/15668394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405095102
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