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Folic Acid Supplementation Delays Atherosclerotic Lesion Development by Modulating MCP1 and VEGF DNA Methylation Levels In Vivo and In Vitro

The pathogenesis of atherosclerosis has been partly acknowledged to result from aberrant epigenetic mechanisms. Accordingly, low folate levels are considered to be a contributing factor to promoting vascular disease because of deregulation of DNA methylation. We hypothesized that increasing the leve...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Cui, Shanshan, Li, Wen, Lv, Xin, Wang, Pengyan, Gao, Yuxia, Huang, Guowei
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454903/
https://ncbi.nlm.nih.gov/pubmed/28475147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050990
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