Melatonin Promotes the In Vitro Development of Microinjected Pronuclear Mouse Embryos via Its Anti-Oxidative and Anti-Apoptotic Effects

CRISPR/Cas9 (Clustered regularly interspaced short palindromic repeats) combined with pronuclear microinjection has become the most effective method for producing transgenic animals. However, the relatively low embryo developmental rate limits its application. In the current study, it was observed t...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Tian, Xiuzhi, Wang, Feng, Zhang, Lu, Ji, Pengyun, Wang, Jing, Lv, Dongying, Li, Guangdong, Chai, Menglong, Lian, Zhengxing, Liu, Guoshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454901/
https://ncbi.nlm.nih.gov/pubmed/28475125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050988
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