Melatonin Promotes the In Vitro Development of Microinjected Pronuclear Mouse Embryos via Its Anti-Oxidative and Anti-Apoptotic Effects

CRISPR/Cas9 (Clustered regularly interspaced short palindromic repeats) combined with pronuclear microinjection has become the most effective method for producing transgenic animals. However, the relatively low embryo developmental rate limits its application. In the current study, it was observed t...

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Publicat a:Int J Mol Sci
Autors principals: Tian, Xiuzhi, Wang, Feng, Zhang, Lu, Ji, Pengyun, Wang, Jing, Lv, Dongying, Li, Guangdong, Chai, Menglong, Lian, Zhengxing, Liu, Guoshi
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454901/
https://ncbi.nlm.nih.gov/pubmed/28475125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050988
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