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Mapping and mutation of the conserved DNA polymerase interaction motif (DPIM) located in the C-terminal domain of fission yeast DNA polymerase δ subunit Cdc27

BACKGROUND: DNA polymerases α and δ play essential roles in the replication of chromosomal DNA in eukaryotic cells. DNA polymerase α (Pol α)-primase is required to prime synthesis of the leading strand and each Okazaki fragment on the lagging strand, whereas DNA polymerase δ (Pol δ) is required for...

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Bibliografische gegevens
Hoofdauteurs: Gray, Fiona C, Pohler, J Richard G, Warbrick, Emma, MacNeill, Stuart A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC545490/
https://ncbi.nlm.nih.gov/pubmed/15579205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-5-21
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