Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis

Japanese encephalitis virus (JEV), a neurotropic flavivirus, annually causes over 30,000 Japanese Encephalitis (JE) cases in East and Southeast Asia. Histone deacetylases (HDACs) modulate lysine acetylation of histones and non-histone proteins, regulating many processes including inflammation and an...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lu, Chien-Yi, Chang, Yi-Chih, Hua, Chun-Hung, Chuang, Chieh, Huang, Su-Hua, Kung, Szu-Hao, Hour, Mann-Jen, Lin, Cheng-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454867/
https://ncbi.nlm.nih.gov/pubmed/28468311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050954
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