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Detecting tissue-specific regulation of alternative splicing as a qualitative change in microarray data

Alternative splicing has recently emerged as a major mechanism of regulation in the human genome, occurring in perhaps 40–60% of human genes. Thus, microarray studies of functional regulation could, in principle, be extended to detect not only the changes in the overall expression of a gene, but als...

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Autores principales: Le, Keith, Mitsouras, Katherine, Roy, Meenakshi, Wang, Qi, Xu, Qiang, Nelson, Stanley F., Lee, Christopher
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC545471/
https://ncbi.nlm.nih.gov/pubmed/15598820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh173
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