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In Vitro and In Vivo Anticancer Activity of Gimatecan against Hepatocellular Carcinoma
OBJECTIVE: Gimatecan is a new camptothecin (CPT) analogue that inhibits tumor growth by targeting DNA topoisomerase I (TOP I) and introducing strong and persistent DNA cleavage. Anti-tumor activity has been demonstrated with a wide range of solid tumors in previous preclinical and clinical studies....
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| Опубликовано в: : | Asian Pac J Cancer Prev |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
West Asia Organization for Cancer Prevention
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5454685/ https://ncbi.nlm.nih.gov/pubmed/28030910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2016.17.11.4853 |
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