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Pa-AGOG, the founding member of a new family of archaeal 8-oxoguanine DNA-glycosylases
Oxidative damage represents a major threat to genomic stability, as the major product of DNA oxidation, 8-oxoguanine (GO), frequently mispairs with adenine during replication. In order to prevent these mutagenic events, organisms have evolved GO-DNA glycosylases that remove this oxidized base from D...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC545463/ https://ncbi.nlm.nih.gov/pubmed/15604455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh995 |
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