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An in vivo strategy to counteract post-administration anticoagulant activity of azido-Warfarin

Drugs, usually long acting and metabolically stable molecules, might be the source of adverse effects triggered by complex drug interactions, anaphylaxis and drug-induced coagulopathy. To circumvent this growing drug safety issue, we herein investigate the opportunity offered by bio-orthogonal chemi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ursuegui, Sylvain, Recher, Marion, Krężel, Wojciech, Wagner, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454458/
https://ncbi.nlm.nih.gov/pubmed/28524847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15242
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