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Looking into DNA recognition: zinc finger binding specificity

We present a quantitative, theoretical analysis of the recognition mechanisms used by two zinc finger proteins: Zif268, which selectively binds to GC-rich sequences, and a Zif268 mutant, which binds to a TATA box site. This analysis is based on a recently developed method (ADAPT), which allows bindi...

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Detalhes bibliográficos
Main Authors: Paillard, Guillaume, Deremble, Cyril, Lavery, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545445/
https://ncbi.nlm.nih.gov/pubmed/15613596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh1003
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