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Octyl glucoside extracts GTP-binding regulatory proteins from rat brain "synaptoneurosomes" as large, polydisperse structures devoid of beta gamma complexes and sensitive to disaggregation by guanine nucleotides.

GTP-binding regulatory proteins are generally purified from cholate-extracted membranes in the form of heterotrimers (G proteins) consisting of a GTP-binding subunit (alpha protein) complexed with a tightly interacted heterodimer termed beta gamma. In this study we extracted the proteins from rat br...

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Збережено в:
Бібліографічні деталі
Опубліковано в::Proc Natl Acad Sci U S A
Автори: Nakamura, S, Rodbell, M
Формат: Artigo
Мова:Inglês
Опубліковано: National Academy of Sciences 1990
Предмети:
Онлайн доступ:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54544/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2117281/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.16.6413
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