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EGF-mediated inhibition of ubiquitin-specific peptidase 24 expression has a crucial role in tumorigenesis

In this study, several cancer-related proteins (Bax, p300, E2F4 and securin) have been proven to be substrates of ubiquitin-specific peptidase 24 (USP24), and relevance has been shown between USP24 and its substrates in samples from clinical lung cancer patients. Silencing USP24 increases the cancer...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Wang, S-A, Wang, Y-C, Chuang, Y-P, Huang, Y-H, Su, W-C, Chang, W-C, Hung, J-J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454318/
https://ncbi.nlm.nih.gov/pubmed/27991932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.445
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