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Electrostatic attraction of weak monoacid anions increases probability for protonation and passage through aquaporins

A positive electrostatic field emanating from the center of the aquaporin (AQP) water and solute channel is responsible for the repulsion of cations. At the same time, however, a positive field will attract anions. In this regard, l-lactate/lactic acid permeability has been shown for various isoform...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Rothert, Monja, Rönfeldt, Deike, Beitz, Eric
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454115/
https://ncbi.nlm.nih.gov/pubmed/28360107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.782516
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