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Large-scale analysis of variation in the insulin-like growth factor family in humans reveals rare disease links and common polymorphisms

The insulin-like growth factors IGF1 and IGF2 are closely related proteins that are essential for normal growth and development in humans and other species and play critical roles in many physiological and pathophysiological processes. IGF actions are mediated by transmembrane receptors and modulate...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Hovedforfatter: Rotwein, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454106/
https://ncbi.nlm.nih.gov/pubmed/28389567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.783639
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