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Large-scale analysis of variation in the insulin-like growth factor family in humans reveals rare disease links and common polymorphisms
The insulin-like growth factors IGF1 and IGF2 are closely related proteins that are essential for normal growth and development in humans and other species and play critical roles in many physiological and pathophysiological processes. IGF actions are mediated by transmembrane receptors and modulate...
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| Udgivet i: | J Biol Chem |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5454106/ https://ncbi.nlm.nih.gov/pubmed/28389567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.783639 |
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