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Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1 RNA.

Many RNA-associated proteins contain a ribonucleoprotein (RNP) consensus octamer encompassed by a conserved 80 amino acid sequence, which we have termed an RNA recognition motif (RRM). RRM family members contain either one (class I) or multiple (class II) copies of this motif. We report here that a...

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Autori principali: Lutz-Freyermuth, C, Query, C C, Keene, J D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC54540/
https://ncbi.nlm.nih.gov/pubmed/1696729
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