Induction of Colonic Regulatory T Cells by Mesalamine by Activating the Aryl Hydrocarbon Receptor

BACKGROUND & AIMS: Mesalamine is a first-line drug for treatment of inflammatory bowel diseases (IBD). However, its mechanisms are not fully understood. CD4(+) Foxp3(+) regulatory T cells (Tregs) play a potential role in suppressing IBD. This study determined whether the anti-inflammatory activi...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Mol Gastroenterol Hepatol
Hauptverfasser: Oh-oka, Kyoko, Kojima, Yuko, Uchida, Koichiro, Yoda, Kimiko, Ishimaru, Kayoko, Nakajima, Shotaro, Hemmi, Jun, Kano, Hiroshi, Fujii-Kuriyama, Yoshiaki, Katoh, Ryohei, Ito, Hiroyuki, Nakao, Atsuhito
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453907/
https://ncbi.nlm.nih.gov/pubmed/28593185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.03.010
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