Intra-articular Recombinant Human Proteoglycan 4 Mitigates Cartilage Damage Following Destabilization of the Medial Meniscus in the Yucatan Minipig

BACKGROUND: Lubricin, or proteoglycan 4 (PRG4), is a glycoprotein responsible for joint boundary lubrication. PRG4 has been previously shown to be down-regulated following traumatic joint injury such as a meniscal tear. There is preliminary evidence suggesting that intra-articular injection of PRG4...

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Detalhes bibliográficos
Publicado no:Am J Sports Med
Main Authors: Waller, Kimberly A., Chin, Kaitlyn E., Jay, Gregory D., Zhang, Ling X., Teeple, Erin, McAllister, Scott, Badger, Gary J., Schmidt, Tannin A., Fleming, Braden C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453820/
https://ncbi.nlm.nih.gov/pubmed/28129516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0363546516686965
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