Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology

Tuberculosis remains a global pandemic and drives lung matrix destruction to transmit. Whilst pathways driving inflammatory responses in macrophages have been relatively well described, negative regulatory pathways are less well defined. We hypothesised that Mycobacterium tuberculosis (Mtb) specific...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Brace, Patience T., Tezera, Liku B., Bielecka, Magdalena K., Mellows, Toby, Garay, Diana, Tian, Shuye, Rand, Lucinda, Green, Justin, Jogai, Sanjay, Steele, Andrew J., Millar, Timothy M., Sanchez-Elsner, Tilman, Friedland, Jon S., Proud, Christopher G., Elkington, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453634/
https://ncbi.nlm.nih.gov/pubmed/28570642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006367
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