Seminal plasma induces inflammation and enhances HIV-1 replication in human cervical tissue explants

The most immediate and evident effect of mucosal exposure to semen in vivo is a local release of proinflammatory mediators accompanied by an influx of leukocytes into the female genital mucosa (FGM). The implication of such response in HIV-1 transmission has never been addressed due to limitations o...

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Publicat a:PLoS Pathog
Autors principals: Introini, Andrea, Boström, Stéphanie, Bradley, Frideborg, Gibbs, Anna, Glaessgen, Axel, Tjernlund, Annelie, Broliden, Kristina
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453613/
https://ncbi.nlm.nih.gov/pubmed/28542587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006402
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