Imatinib attenuates cardiac fibrosis by inhibiting platelet-derived growth factor receptors activation in isoproterenol induced model

Cardiac fibrosis is a significant global health problem with limited treatment choices. Although previous studies have shown that imatinib (IMA) inhibited cardiac fibrosis, the anti-fibrotic mechanisms have not been clearly uncovered. The aim of this study is to evaluate whether IMA attenuates cardi...

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Udgivet i:PLoS One
Main Authors: Wang, Le-Xun, Yang, Xiao, Yue, Yuan, Fan, Tian, Hou, Jian, Chen, Guang-Xian, Liang, Meng-Ya, Wu, Zhong-Kai
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453565/
https://ncbi.nlm.nih.gov/pubmed/28570599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178619
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