Rectal administration of a chlamydial subunit vaccine protects against genital infection and upper reproductive tract pathology in mice

In this study, we tested the hypothesis that rectal immunization with a VCG-based chlamydial vaccine would cross-protect mice against heterologous genital Chlamydia trachomatis infection and Chlamydia-induced upper genital tract pathologies in mice. Female mice were immunized with a C. trachomatis s...

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Foilsithe in:PLoS One
Main Authors: Pais, Roshan, Omosun, Yusuf, He, Qing, Blas-Machado, Uriel, Black, Carolyn, Igietseme, Joseph U., Fujihashi, Kohtaro, Eko, Francis O.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453548/
https://ncbi.nlm.nih.gov/pubmed/28570663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178537
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