Systemic activation of Toll-like receptor 2 suppresses mitochondrial respiration and exacerbates hypoxic–ischemic injury in the developing brain

Infection and inflammation are known risk factors for neonatal brain injury. Mycoplasma and Gram-positive bacteria, for which Toll-like receptor 2 (TLR2) plays a key role in recognition and inflammatory response, are among the most common pathogens in the perinatal period. Here, we report that syste...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cereb Blood Flow Metab
Päätekijät: Mottahedin, Amin, Svedin, Pernilla, Nair, Syam, Mohn, Carl-Johan, Wang, Xiaoyang, Hagberg, Henrik, Ek, Joakim, Mallard, Carina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: SAGE Publications 2017
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453473/
https://ncbi.nlm.nih.gov/pubmed/28139935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17691292
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