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Reduction of miR-21 induces SK-N-SH cell apoptosis and inhibits proliferation via PTEN/PDCD4

MicroRNA (miR/miRNA)-21 is a well-known oncogenic miRNA that is overexpressed in various types of tumors. The tumor-suppressor genes programmed cell death 4 (PDCD4) and phosphatase tensin homologue (PTEN), are targets of miR-21, and are underexpressed in several types of cancer. However, the express...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Wang, Zuopeng, Yao, Wei, Li, Kai, Zheng, Na, Zheng, Chao, Zhao, Xiaolong, Zheng, Shan
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452970/
https://ncbi.nlm.nih.gov/pubmed/28599474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6052
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