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Synergistic activity of the histone deacetylase inhibitor trichostatin A and the proteasome inhibitor PS-341 against taxane-resistant ovarian cancer cell lines

Although a combination of platinum- and taxane-based chemotherapy is recommended for at least 70% patients with ovarian cancer as treatment subsequent to surgery, the initial response to the chemotherapy is not durable and tumors become resistant. Histone deacetylase and proteasome inhibitors are no...

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Dettagli Bibliografici
Pubblicato in:Oncol Lett
Autori principali: Jin, Xin, Fang, Yong, Hu, Yi, Chen, Jing, Liu, Wei, Chen, Gang, Gong, Mei, Wu, Peng, Zhu, Tao, Wang, Shixuan, Zhou, Jianfeng, Wang, Hui, Ma, Ding, Li, Kezhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452869/
https://ncbi.nlm.nih.gov/pubmed/28588720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6032
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