A complement-microglial axis drives synapse loss during virus-induced memory impairment

Over 50% of patients who survive neuroinvasive infection with West Nile virus (WNV) exhibit chronic cognitive sequelae(1,2). Although thousands of cases of WNV-mediated memory dysfunction accrue annually(3), the mechanisms responsible for these impairments are unknown. The classical complement casca...

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Publicado no:Nature
Main Authors: Vasek, Michael J., Garber, Charise, Dorsey, Denise, Durrant, Douglas M., Bollman, Bryan, Soung, Allison, Yu, Jinsheng, Perez-Torres, Carlos, Frouin, Arnaud, Wilton, Daniel K., Funk, Kristen, DeMasters, Bette K., Jiang, Xiaoping, Bowen, James R., Mennerick, Steven, Robinson, John K., Garbow, Joel R., Tyler, Kenneth L., Suthar, Mehul S., Schmidt, Robert E., Stevens, Beth, Klein, Robyn S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452615/
https://ncbi.nlm.nih.gov/pubmed/27337340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18283
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