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Drug delivery in a tumour cord model: a computational simulation

The tumour vasculature and microenvironment is complex and heterogeneous, contributing to reduced delivery of cancer drugs to the tumour. We have developed an in silico model of drug transport in a tumour cord to explore the effect of different drug regimes over a 72 h period and how changes in phar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:R Soc Open Sci
Hauptverfasser: Hubbard, M. E., Jove, M., Loadman, P. M., Phillips, R. M., Twelves, C. J., Smye, S. W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society Publishing 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451806/
https://ncbi.nlm.nih.gov/pubmed/28573005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.170014
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