ERBB signaling attenuates proinflammatory activation of nonclassical monocytes

Immune activation in chronic systolic heart failure (HF) correlates with disease severity and prognosis. Recombinant neuregulin-1 (rNRG-1) is being developed as a possible therapy for HF, based on the activation of ERBB receptors in cardiac cells. Work in animal models of HF led us to hypothesize th...

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Publicado en:Am J Physiol Heart Circ Physiol
Autores principales: Ryzhov, Sergey, Matafonov, Anton, Galindo, Cristi L., Zhang, Qinkun, Tran, Truc-Linh, Lenihan, Daniel J., Lenneman, Carrie Geisberg, Feoktistov, Igor, Sawyer, Douglas B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451588/
https://ncbi.nlm.nih.gov/pubmed/28235789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00486.2016
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