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Long-term HIF-1α transcriptional activation is essential for heat-acclimation-mediated cross tolerance: mitochondrial target genes

An important adaptive feature of heat acclimation (HA) is the induction of cross tolerance against novel stressors (HACT) Reprogramming of gene expression leading to enhanced innate cytoprotective features by attenuating damage and/or enhancing the response of “help” signals plays a pivotal role. Hy...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Alexander-Shani, Rivka, Mreisat, Ahmad, Smeir, Elia, Gerstenblith, Gary, Stern, Michael D., Horowitz, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451574/
https://ncbi.nlm.nih.gov/pubmed/28274939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00461.2016
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