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A model of chronic diabetic polyneuropathy: benefits from intranasal insulin are modified by sex and RAGE deletion

Human diabetic polyneuropathy (DPN) is a progressive complication of chronic diabetes mellitus. Preliminary evidence has suggested that intranasal insulin, in doses insufficient to alter hyperglycemia, suppresses the development of DPN. In this work we confirm this finding, but demonstrate that its...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: de la Hoz, Cristiane L., Cheng, Chu, Fernyhough, Paul, Zochodne, Douglas W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451527/
https://ncbi.nlm.nih.gov/pubmed/28223295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00444.2016
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