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A model of chronic diabetic polyneuropathy: benefits from intranasal insulin are modified by sex and RAGE deletion

Human diabetic polyneuropathy (DPN) is a progressive complication of chronic diabetes mellitus. Preliminary evidence has suggested that intranasal insulin, in doses insufficient to alter hyperglycemia, suppresses the development of DPN. In this work we confirm this finding, but demonstrate that its...

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Vydáno v:Am J Physiol Endocrinol Metab
Hlavní autoři: de la Hoz, Cristiane L., Cheng, Chu, Fernyhough, Paul, Zochodne, Douglas W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451527/
https://ncbi.nlm.nih.gov/pubmed/28223295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00444.2016
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