Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction

Pulmonary vascular disease is characterized by remodeling and loss of microvessels and is typically attributed to pathological responses in vascular endothelium or abnormal smooth muscle cell phenotypes. We have challenged this understanding by defining an adult pulmonary mesenchymal progenitor cell...

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發表在:J Clin Invest
Main Authors: Gaskill, Christa F., Carrier, Erica J., Kropski, Jonathan A., Bloodworth, Nathaniel C., Menon, Swapna, Foronjy, Robert F., Taketo, M. Mark, Hong, Charles C., Austin, Eric D., West, James D., Means, Anna L., Loyd, James E., Merryman, W. David, Hemnes, Anna R., De Langhe, Stijn, Blackwell, Timothy S., Klemm, Dwight J., Majka, Susan M.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2017
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451236/
https://ncbi.nlm.nih.gov/pubmed/28463231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88629
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