Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction

Pulmonary vascular disease is characterized by remodeling and loss of microvessels and is typically attributed to pathological responses in vascular endothelium or abnormal smooth muscle cell phenotypes. We have challenged this understanding by defining an adult pulmonary mesenchymal progenitor cell...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Gaskill, Christa F., Carrier, Erica J., Kropski, Jonathan A., Bloodworth, Nathaniel C., Menon, Swapna, Foronjy, Robert F., Taketo, M. Mark, Hong, Charles C., Austin, Eric D., West, James D., Means, Anna L., Loyd, James E., Merryman, W. David, Hemnes, Anna R., De Langhe, Stijn, Blackwell, Timothy S., Klemm, Dwight J., Majka, Susan M.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451236/
https://ncbi.nlm.nih.gov/pubmed/28463231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88629
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