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Inflammasomes and IL-1 biology in the pathogenesis of allograft dysfunction

Inflammasomes are high-molecular-weight cytosolic complexes that mediate the activation of caspases. There are many inflammasomes, and each is influenced by a unique pattern-recognition receptor response. Two signals are typically involved in the inflammasome pathways. Signal one involves recognitio...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Weigt, S. Samuel, Palchevskiy, Vyacheslav, Belperio, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451233/
https://ncbi.nlm.nih.gov/pubmed/28569730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93537
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