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Metaphase chromosome structure is dynamically maintained by condensin I-directed DNA (de)catenation

Mitotic chromosome assembly remains a big mystery in biology. Condensin complexes are pivotal for chromosome architecture yet how they shape mitotic chromatin remains unknown. Using acute inactivation approaches and live-cell imaging in Drosophila embryos, we dissect the role of condensin I in the m...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Piskadlo, Ewa, Tavares, Alexandra, Oliveira, Raquel A
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451211/
https://ncbi.nlm.nih.gov/pubmed/28477406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26120
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