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Upregulation of CB(2) receptors in reactive astrocytes in canine degenerative myelopathy, a disease model of amyotrophic lateral sclerosis

Targeting of the CB(2) receptor results in neuroprotection in the SOD1(G93A) mutant mouse model of amyotrophic lateral sclerosis (ALS). The neuroprotective effects of CB(2) receptors are facilitated by their upregulation in the spinal cord of the mutant mice. Here, we investigated whether similar CB...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Fernández-Trapero, María, Espejo-Porras, Francisco, Rodríguez-Cueto, Carmen, Coates, Joan R., Pérez-Díaz, Carmen, de Lago, Eva, Fernández-Ruiz, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451172/
https://ncbi.nlm.nih.gov/pubmed/28069688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.028373
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